![]() The condition can be fatal if left untreated. Another complication in 25-30% of patients is increased risk of cancer malignancies, primarily adenocarcinoma in the gastrointestinal and genital mucosa and lungs. The disease can also impact mucous membranes in the nose, throat, genitals and anus, causing severe, irreversible damage. Scarring of ocular mucosa, present in half of patients, may lead to blindness. Oral mucosa - gums, inner lining of the cheeks and lips, palate and tongue - are involved in 80-90% of cases. Anti-laminin 332 MMP lesions often scar and can lead to serious complications depending on the mucosal surfaces affected. MMP is an autoimmune blistering disease characterized by multisite lesions on mucous membranes. ![]() “The innovative methods he established for diagnosing autoimmune blistering diseases are used worldwide, and we are proud to continue his legacy.” ( which counts Beutner among its clinical laboratories. Lakshmanan Suresh, Technical Director at Beutner and Chief Medical Officer of KSL Diagnostics, Inc. Ernst Beutner, the father of immunodermatology,” said Dr. ![]() “The development and launch of Beutner’s much-anticipated serological assay for laminin 332 MMP builds on the pioneering work of Dr. Long sought after by oral pathologists, oral surgeons, periodontists and dentists, in addition to dermatologists, Beutner’s laminin 332-specific serological assay reduces the time to confirmed diagnosis from as much as two years to 72 hours or less. Without a definitive interpretation, patients experience considerable pain and suffering due to misdiagnosis and treatment delays. On JKSL Beutner Laboratories (Beutner), a global leader in immunologic testing for the diagnosis of bullous, vascular, connective tissue and inherited skin diseases, announced the launch of a first-to-market indirect immunofluorescence (IIF) serum blood test in the U.S. that positively identifies laminin 332, an antigen associated with the chronic, debilitating autoimmune disease mucous membrane pemphigoid (MMP). Highly accurate IIF serological assay for Laminin 332 Mucous Membrane Pemphigoid reduces the wait for confirmed diagnosis from months or years to 72 hours or less
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